Abstract As climate change intensifies, endemic plants native to South Korea, especially those in specialized ecological niches, confront heightened risks of distribution shifts and habitat degradation. To provide a comprehensive understanding of these impacts, this study evaluates the climate-induced distribution dynamics and niche adaptation of these endemic species across the entire Korean Peninsula. Utilizing species distribution models (SDMs) for 179 plant species and incorporating environmental variables under projected future climate scenarios, our analysis identified unique distribution and niche adaptation patterns. Findings demonstrate that specialized endemic species are likely to migrate to higher altitudes and latitudes, highlighting their distinct vulnerability due to limited ecological niches. Our comparative approach underscores the necessity for refined conservation strategies that address the specific requirements of these endemic species, as opposed to those with wider distributions. This research offers valuable insights into biodiversity conservation amid climate change, proposing targeted actions such as the establishment of protected areas, habitat restoration, and the implementation of assisted migration strategies to safeguard these vital endemic plant species throughout the Korean Peninsula. Introduction The investigation of endemic plant species, defined as flora exclusive to, often secluded areas, is pivotal for global biodiversity conservation efforts 1 . In particular, the endemic flora of the Korean Peninsula stands out as a unique fragment of global vegetation, unmatched anywhere else 2 . These plants play a crucial role in sustaining ecological equilibrium and preserving the distinctive features of their habitats 3 , 4 . Their conservation transcends ecological interests, entering the realm of national bio-sovereignty, particularly highlighted by the Nagoya Protocol under the Convention on Biological Diversity (CBD), which stresses the importance of Access and Benefit-Sharing (ABS) of genetic resources. Endemic species are prized for their unique genetic compositions and adaptations to distinct ecological niches, making them invaluable assets. Beyond their local significance, […]